SLC16A13 (L423) polyclonal Antibody | BS3143

SLC16A13 (L423) polyclonal Antibody | BS3143 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC16A13 (L423) polyclonal Antibody detects endogenous levels of SLC16A13 protein.

Molecular Weight: ~ 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13; SLC16A13; MCT13

Immunogen: Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: