SLC29A2 Antibody | 8127

SLC29A2 Antibody | 8127 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Rat: (100%)

Immunogen: SLC29A2 antibody was raised against a 19 amino acid peptide near the center of human SLC29A2.
The immunogen is located within amino acids 250 - 300 of SLC29A2.

Research Area: Cancer, Homeostasis

Tested Application: E, WB, IHC-P, IF

Application: SLC29A2 antibody can be used for detection of SLC29A2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins.

Positive Control 1: Cat. No. 1310 - Human Bladder Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 50 kDa
Observed: 50 kDa

Validation: N/A

Isoform: N/A

Purification: SLC29A2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SLC29A2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SLC29A2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Solute carrier family 29 member 2, Equilibrative nucleoside transporter 2, ENT2, DER12, HNP36

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1, 2) . SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3) . As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4) .