SLC34A1 polyclonal Antibody | BS8402

SLC34A1 polyclonal Antibody | BS8402 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na (+) /P (i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells . NPT2 gene expression is crucial for PTH effects on renal P (i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC34A1 polyclonal Antibody detects endogenous levels of SLC34A1 protein.

Molecular Weight: ~ 72 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Sodium-dependent phosphate transport protein 2A; Sodium-phosphate transport protein 2A; Na (+) -dependent phosphate cotransporter 2A; NaPi-3; Sodium/phosphate cotransporter 2A; Na (+) /Pi cotransporter 2A; NaPi-2a; Solute carrier family 34 member 1; SLC34A1; NPT2; SLC17A2

Immunogen: Recombinant protein of human SLC34A1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Actin Dynamics,Adherens Junction signaling,Regulation of Apoptosis,Regulation of Microtubule Dynamics,TGFβ Smad signaling,