SLC4A11 polyclonal Antibody | BS61729

SLC4A11 polyclonal Antibody | BS61729 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity) . Involved in borate homeostasis. In the absence of borate, it functions as a Na (+) and OH (-) (H (+) ) channel. In the presence of borate functions as an electrogenic Na (+) coupled borate cotransporter.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SLC4A11 polyclonal Antibody detects endogenous levels of SLC4A11 protein.

Molecular Weight: ~ 99 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Sodium bicarbonate transporter-like protein 11; Bicarbonate transporter-related protein 1; Sodium borate cotransporter 1; NaBC1; Solute carrier family 4 member 11; SLC4A11; BTR1

Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human SLC4A11.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Warburg Effect,