SLC7A9 Antibody | XW-8130

SLC7A9 Antibody | XW-8130 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 3-19

Research Area: Other

Tested Application: WB

Application: B (0, +) -type amino acid transporter 1 antibody can be used for the detection of B (0, +) -type amino acid transporter 1 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 53.5 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: SLC7A9 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: BAT1Solute carrier family 7 member 9, BAT1, CSNU3, B (0, +) type amino acid transporter 1, +) AT, Glycoprotein-associated amino acid transporter b0, +AT1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b (0, +) -like activity) . Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.

DISEASE: Defects in SLC7A9 are a cause of non-type I cystinuria (CSNU) [MIM:600918]. CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent) ; type II (high excretor) ; type III (moderate excretor) . Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non-classic type I cystinuria cases.