SMARCAD1 polyclonal Antibody | BS7898

SMARCAD1 polyclonal Antibody | BS7898 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Background: Smarcad1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1), also known as ETL1 or HEL1, is a 1,026 amino acid nuclear protein suggested to function as an ATPdependent DNA helicase. A member of the SNF2/RAD54 helicase family, Smarcad1 undergoes post-translational phosphorylation by either ATM or ATR and contains one helicase C-terminal domain, a helicase ATP-binding domain and two CUE domains. Existing as two alternatively spliced isoforms, Smarcad1 is encoded by a gene that maps to human chromosome 4, which represents approximately 6% of the human genome, contains nearly 900 genes and is associated with Huntington’s disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SMARCAD1 polyclonal Antibody detects endogenous levels of SMARCAD1 protein.

Molecular Weight: ~ 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATP dependent helicase 1; ATP-dependent helicase 1; ETL1; hHEL1; Smarcad1; SMRCD_HUMAN; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1;

Immunogen: Recombinant full length Human SMARCAD1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: