SMARCC1 polyclonal Antibody | BS91257

SMARCC1 polyclonal Antibody | BS91257 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Application: WB ICC IF FC IP

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50

Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) . During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SMARCC1 polyclonal Antibody detects endogenous levels of SMARCC1 protein.

Molecular Weight: 123 kDa (Predicted band size) 150 kDa (Observed band size)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BAF155, SMARCC1, AI115498, BAF 155, BAF155, BRG 1 associated factor 155, BRG1 associated factor 155, BRG1-associated factor 155, Chromatin remodeling complex BAF155 subunit, CRACC 1, CRACC1, Mammalian chromatin remodeling complex BRG 1 associated factor 155, Mammalian chromatin remodeling complex BRG1 associated factor 155, Rsc 8, Rsc8, SMARC C1, SMARCC 1, SMARCC1, SMRC1, SRG 3, SRG3, SWI 3, SWI/SNF complex 155 kDa subunit, SWI/SNF complex subunit SMARCC1, SWI/SNF related matrix associated actin dependent regulator of chromatin c1, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, SWI3,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: