LBD
SNRPD3 Antibody (C-term) [APR32682G]
- SKU:
- LBD-APR32682G
- Availability:
- Usually ships in 5 working days
Description
SNRPD3 Antibody (C-term) [APR32682G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SNRPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the C-terminal region of human SNRPD3.
Cellular Localisation: Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes
Molecular Weight: 13916
Clone: Polyclonal
Gene Name: SNRPD3
Gene ID: 6634
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Is also a component of the minor U12 spliceosome (PubMed:15146077) . As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50 IHC-P--1:100
Synonyms: Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3, SNRPD3