SNRPN Antibody | 8155

SNRPN Antibody | 8155 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%) , Chicken: (95%)

Immunogen: SNRPN antibody was raised against a 20 amino acid peptide near the amino terminus of human SNRPN.
The immunogen is located within amino acids 30 - 80 of SNRPN.

Research Area: Homeostasis

Tested Application: E, WB, IHC-P, IF

Application: SNRPN antibody can be used for detection of SNRPN by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: SNRPN antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1208 - THP-1 Cell Lysate

Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 26 kDa
Observed: 25 kDa

Validation: N/A

Isoform: N/A

Purification: SNRPN antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SNRPN antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SNRPN antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Small nuclear ribonucleoprotein-associated protein N, HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The small nuclear riboprotein-associated protein N (SNRPN) is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN plays a role in pre-mRNA processing and alternative splicing (1) . SNRPN arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF) (2) . Mutations or deletions in the SNRPN gene may be linked to responsible for Angelman syndrome or Prader-Willi syndrome (3) .