SOX11 polyclonal Antibody | BS91273

SOX11 polyclonal Antibody | BS91273 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IP

Application Range: WB:1:500-1:1,000 ICC:1:50-1:200

Background: The Sox family are comprised of members that are related to the mammalian sex determining gene SRY. The Sox family of genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been conserved during evolution and play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-11 (SRY (sex determining region Y) -box 11) is a 441 amino acid nuclear protein expressed mainly in the nervous system. Containing an HMG box DNA-binding domain, Sox-11 may play a critical role in the developing nervous system.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SOX11 polyclonal Antibody detects endogenous levels of SOX11 protein.

Molecular Weight: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SOX11, MRD27, SOX11, SOX11, SRY (sex determining region Y) box 11, SRY related HMG box gene 11, SRY-box 11, Transcription factor SOX-11,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: