Sox2 monoclonal Antibody | MB0064

Sox2 monoclonal Antibody | MB0064 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse

Application: WB ICC FC

Application Range: WB: 1:1000 ICC: 1:50~200 FC: 1:50~100

Background: SOX 2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX 2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of Sox2 and does not cross-react with related proteins

Molecular Weight: Predicted band size:35KDa Observed band size:35KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Transcription factor SOX-2

Immunogen: Recombinant full length Human Sox2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: