Cell-permeable. A selective inhibitor of c-Jun N-terminal kinase (JNK). Competitively and reversibly inhibits JNK1, 2 and 3 (IC₅₀ = 40-90 nM) with negligible activity at ERK2, p38β and a range of...
A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.U0126 is a potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2...