Spectrin β II polyclonal Antibody | BS71517

Spectrin β II polyclonal Antibody | BS71517 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:1000 - 1:3000

Background: Beta Fodrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. Beta Fodrin is one member of a family of beta-spectrin proteins. This protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Spectrin β II polyclonal Antibody detects endogenous levels of Spectrin β II protein.

Molecular Weight: ~ 275 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SPTBN1;ELF;SPTB2;betaSpII;

Immunogen: A synthetic peptide of human SPTBN1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,