SPG7 monoclonal Antibody | MB65230

SPG7 monoclonal Antibody | MB65230 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:2000

Background: This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: SPG7, paraplegin matrix AAA peptidase subunit

Molecular Weight: 88.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CAR; CMAR; PGN; SPG5C

Immunogen: Human recombinant protein fragment correspongding to amino acids 300-573 of human SPG7 (NP_003110) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A