SQ 22536 | 2019

Cell-permeable. SQ 22,536 is an adenylyl cyclase inhibitor. (IC₅₀ = 1.4 μM). It inhibits cAMP production induced by prostaglandin E1 in platelet lysates (IC₅₀ = 82 µM) and in intact platelets (IC₅₀ = 1 µM).

SQ 22,536 is an adenylyl cyclase inhibitor. (IC₅₀ = 1.4 μM). It inhibits cAMP production induced by prostaglandin E1 in platelet lysates (IC₅₀ = 82 µM) and in intact platelets (IC₅₀ = 1 µM).

2019 | SQ 22536 DataSheet

Alternate Name/Synonyms: 9-(Tetrahydrofuran-2-yl)-9H-purin-6-amine; 9-THF-Ade

Appearance: Off-white solid

Formulation: N/A

CAS Number: 17318-31-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₁₁N₅O

Molecular Weight: 205.22

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO (>10 mg/ml) or H₂O (>10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent adenylyl cyclase inhibitor

MDL Number: MFCD00210216

PubChem CID: 5270

SMILES: C1CC(OC1)N2C=NC3=C2N=CN=C3N

InChi: InChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12)

InChi Key: UKHMZCMKHPHFOT-UHFFFAOYSA-N