SR1001 | 1902

Cell-permeable. A high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice.

SR1001 is a high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice.

1902 | SR1001 DataSheet

Alternate Name/Synonyms: N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide

Appearance: Cream solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₃F₆N₃O₄S₂

Molecular Weight: 477.4

Cell-Permeable?: Yes

Purity: ≥98% by TLC and NMR

Solubilities: DMSO (10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A high affinity synthetic ligand to retinoic acid-related orphan receptors ɑ (RORɑ) and γt

MDL Number: N/A

PubChem CID: N/A

SMILES: N/A

InChi: N/A

InChi Key: N/A