STAB2 Antibody | 13-413

STAB2 Antibody | 13-413 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_060034.9) .

Research Area: Cell Cycle, Signal Transduction, Stem Cell

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: BT-474

Positive Control 3: Mouse liver

Positive Control 4: Mouse eye

Positive Control 5: Mouse kidney

Positive Control 6: Rat liver

Molecular Weight: Observed: 277kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: FEEL2, FELE-2, FELL2, FEX2, HARE, SCARH1, stabilin-2, CD44-like precursor FELL, FAS1 EGF-like and X-link domain containing adhesion molecule-2, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2, hepatic hyaluronan clearance receptor, hyaluronan receptor for endocytosis, hyaluronic acid receptor for endocytosis

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF) -like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.