STAG3 (Q1187) polyclonal Antibody | BS2375

STAG3 (Q1187) polyclonal Antibody | BS2375 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Stromalins are a group of highly conserved proteins that are characterized by the stromalin conservative domain. Stromal antigen 3 (STAG3) is a nuclear protein that is expressed specifically in germinal cells. STAG3 associates with the synaptonemal complex (SC) via immunolocalization. The SC is a meiotic protein structure that aids in the pairing of homologous chromosomes. In mammals, STAG3 associates with the SC and assists in sister chromatid cohesion, which keeps the homologous chromosomes appropriately aligned during the pachytene stage of prophase I. STAG3 appears to be located at the interchromatid domain during metaphase I, but is undetectable in ana-phase I or any of the later stages of meiosis.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STAG3 (Q1187) polyclonal Antibody detects endogenous levels of STAG3 protein.

Molecular Weight: ~ 139 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cohesin subunit SA-3; SCC3 homolog 3; Stromal antigen 3; Stromalin-3; STAG3

Immunogen: Synthetic peptide, corresponding to amino acids 1156-1200 of Human STAG3.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A