Staphylococcal Protein A | IMS02-008-333

Staphylococcal Protein A | IMS02-008-333 | Gentaur UK, US & Europe Distribution

Immunogen: Purified, recombinant Protein A from GE Healthcare, product number 17-0872

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified IgY in 0, 9% NaCl, 0, 1% sodium azide., pH 7.2.

Format: Liquid

Tested Application: Affinity purified IgY

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Recommended Dilutions: 1 : 500 as a capture antibody (ELISA), 1 : 2000 as a detection antibody (ELISA), 1: 1000 (WB)

Molecular weight: 55 | 47 kDa

Confirmed Reactivity: Staphylococcus aureus

Predicted Reactivity: Staphylococcus aureus

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: One precipitation arc in immunodiffusion against Staphylococcal Protein A

Background: Protein A is a surface protein of S. aureus which binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.

Reconstitution: N/A

Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Bacteria

Research Area: Pathology, Staphylococcus