STK31 polyclonal Antibody | BS60242

STK31 polyclonal Antibody | BS60242 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Protein kinases catalyze the post-translational transfer of a phosphate group from ATP to a serine, threonine or tyrosine residue, thereby playing a major role in many intracellular and intercellular signaling cascades. STK31 (Serine/threonine-protein kinase 31) is a 1019 amino acid protein belonging to the protein kinase superfamily. STK31 contains one C-terminal protein kinase domain and one N-terminal Tudor domain, which functions as a protein-protein interaction motif during RNA metabolism or transport. As a testis-specific kinase, STK31 is found in both post-meitoic spermatocytes as well as in mature spermatozoa and is thought to be involved in spermatogensis and/or sperm function. Also, as a result of frequent expression in colorectal, gastric and esophageal cancers, STK31 has been identified as a potential cancer/testis (CT) antigen. There are two named isoforms of STK31 which are produced as a result of an alternative splicing event.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STK31 polyclonal Antibody detects endogenous levels of STK31 protein.

Molecular Weight: ~ 116 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Serine/threonine-protein kinase 31; Serine/threonine-protein kinase NYD-SPK; Sugen kinase 396; SgK396; SGK396

Immunogen: A synthetic peptide corresponding to residues in Human STK31.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: