STYK1 Antibody (N-term) [APR06004G]

STYK1 Antibody (N-term) [APR06004G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This STYK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human STYK1.

Cellular Localisation: Membrane; Single-pass membrane protein

Molecular Weight: 47577

Clone: Polyclonal

Gene Name: STYK1

Gene ID: 55359

Function: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity) .

Summary: Tissue Location: Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431) . Undetectable in most normal lung tissues, widely expressed in lung cancers

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, Protein PK-unique, Serine/threonine/tyrosine kinase 1, STYK1, NOK