Suc-Leu-Leu-Val-Tyr-AMC | 1833

A widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.

Suc-Leu-Leu-Val-Tyr-AMC is a widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.

1833 | Suc-Leu-Leu-Val-Tyr-AMC DataSheet

Alternate Name/Synonyms: Suc-LLVY-AMC; Proteasome Substrate; Calpain Substrate

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: 94367-21-2

Structure Available?: Yes

Peptide sequence: Suc-Leu-Leu-Val-Tyr-AMC

Salt Form: No

Molecular Formula: C₄₀H₅₃N₅O₁₀

Molecular Weight: 763.88

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 5 mM)

Handling: Protect from moisture and light

Country of Origin: USA

Tag Line: A proteasome substrate

MDL Number: MFCD00080248

PubChem CID: 10234210

SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CCC(=O)O

InChi: InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37 (51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48, 49)/t29-,30-,31-,36-/m0/s1

InChi Key: UVFAEQZFLBGVRM-MSMWPWNWSA-N