Sutimlimab (C1S) Antibody, Monoclonal | 10-884

Sutimlimab (C1S) Antibody, Monoclonal | 10-884 | Gentaur UK, US & Europe Distribution

Host: N/A

Reactivity: N/A

Homology: N/A

Immunogen: Chimeric, Humanized / C1S [Homo sapiens]

Research Area: Drug Analogues

Tested Application: N/A

Application: N/A

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: >95%

Clonality: Monoclonal

Clone: N/A

Isotype: IgG4-kappa

Conjugate: Unconjugated

Physical State: N/A

Buffer: PBS buffer pH7.5

Concentration: N/A

Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.

Alternate Name: BIVV009, IPN-009, TNT009

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Sutimlimab is anti-C1s antibody, and studies have shown that it can significantly increase hemoglobin levels in patients with primary cold agglutinin disease. Cold agglutinin disease (CAD) is an acquired autoimmune hemolytic anemia (AIHA) . In cold environments, clinical symptoms related to erythrocyte agglutination occur in cold parts of the body (for example, net Cyanosis or cyanosis of extremities) and hemolytic anemia.