Syndecan 4 Antibody | 33-003

Syndecan 4 Antibody | 33-003 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: A recombinant protein fragment from the N-terminal region of human Syndecan 4 was used as the immunogen for this antibody.

Research Area: Cancer, Neuroscience, Signal Transduction

Tested Application: WB

Application: Western blot: 2-5 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein A affinity chromatography

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.5 mg/mL

Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.

Alternate Name: Syndecan-4, SYND4, Amphiglycan, Ryudocan core protein, SDC4

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: Syndecans are a family of four transmembrane proteoglycans divided into two subfamilies based on transmembrane and cytoplasmic domain similarity: Syndecan 1/3 and 2/4. Via their covalently attached heparan sulphate chains, they bind a variety of ligands and play a role in a number of cell functions including adhesion, proliferation and migration. Syndecan 4 is highly expressed on the cell surface of epithelial cells and fibroblasts and plays an important role in tissue repair. Integrin-mediated binding of fibronectin to Syndecan-4 induces focal adhesions and formation of cytoskeletal stress fibers, facilitating wound healing.