SYNE3 polyclonal Antibody | BS72153

SYNE3 polyclonal Antibody | BS72153 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SYNE3 polyclonal Antibody detects endogenous levels of SYNE3 protein.

Molecular Weight: 112kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: C14orf139; C14orf49; KASH3; LINC00341; NCRNA00341; NET53; Nesp3; Nesprin3; Nesprin 3; Nesprin-3

Immunogen: Recombinant Protein of human SYNE3

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: