T0901317 | B1636

T0901317 is a potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors), with EC50 of ~50 nM and 5 μM, respectively, inhibits nuclear factor/κB (NF/κB).

T0901317 is a potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors), with EC50 of ~50 nM and 5 μM, respectively, inhibits nuclear factor/κB (NF/κB).

B1636 | T0901317 DataSheet

Alternate Name/Synonyms: T0901317; T-0901317; T 0901317; N-(2,2,2-trifluoro-ethyl)-N-[4-(2,2,2-tri- fluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]- benzenesulfonamide; LXR and FXR agonist

Appearance: Solid

Formulation: N/A

CAS Number: 293754-55-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₂NSO₃F₉

Molecular Weight: 481.33

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors)

MDL Number: MFCD03412028

PubChem CID: 447912

SMILES: C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O

InChi: 1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2

InChi Key: SGIWFELWJPNFDH-UHFFFAOYSA-N