TAC1 polyclonal Antibody | BS60380

TAC1 polyclonal Antibody | BS60380 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The tachykinin familyconsists of amidated neuropeptidesthatshare a carboxyterminalsequence (Phe-X-Gly-Leu-Met-NH2) . Preprotachykinin I, also designated protachykinin 1 precursor (PPT), is a common precursor of tachykinins. Preprotachykinin I alternatelysplicesto formvariousisoforms. These isoforms include: Substance P; Neurokinin A (NKA, Substance K, Neuromedin L) ; Neurokinin B;Neuropeptide K (NPK) ;Neuropeptide γ; and C-terminal flanking peptide. Substance P is expressesed primarilyin the small diameter primary sensoryfibers of the peripheral nervoussystem, and in the superficial dorsal horn of the spinalcord, the substantia nigra, and the medial amygdaloid nucleus of the central nervoussystem. Tachykinin peptides havemany plieotropicfunctionsincluding: neurotransmission, immune/ hematopoieticmodulation, angiogenesis andmitogenesis. Preprotachykinin I has been implicated in breastcancer and bonemarrowmetastasis. Substance P plays a role in depression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TAC1 polyclonal Antibody detects endogenous levels of TAC1 protein.

Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protachykinin-1; PPT; Substance P; Neurokinin A; NKA; Neuromedin L; Substance K; Neuropeptide K; NPK ;Neuropeptide gamma; C-terminal-flanking peptide; TAC1; NKA, NKNA, TAC2

Immunogen: A synthetic peptide corresponding to residues in Human TAC1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Hypoxia Signaling,Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,