TARBP2 Antibody | 29-327

TARBP2 Antibody | 29-327 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Zebrafish

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TARBP2.

Research Area: Cancer

Tested Application: E, WB

Application: TARBP2 antibody can be used for detection of TARBP2 by ELISA at 1:312500. TARBP2 antibody can be used for detection of TARBP2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 8 kDa, 37 kDa, 39 kDa, 37 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by protein A chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store TARBP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: TARBP2, LOQS, TRBP, TRBP1, TRBP2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS) , contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARBP2 binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein.