Additional Information
Size: |
100 µl |
Target: |
Tau (pSer422) |
Conjugate: |
Biotin |
Research Area: |
Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Cell Signaling | Cytoskeleton | Microtubules | MT Associated Proteins | Neuroscience | Cell Markers | Neuron Markers | Axon Markers |
Alternative Name: |
Neurofibrillary tangle protein Antibody, MAPTL Antibody, Microtubule-associated protein tau Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody, PHF-tau Antibody, MAPT Antibody |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human Tau around the phosphorylation site of serine 422 (pSer422). |
Immunogen Species: |
Human |
Applications: |
WB, IHC |
Host: |
Rabbit |
Isotype: |
IgG |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:1000); IHC (1:25-1:100); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of Tau only when phosphorylated at serine 422 (pSer422). Detects a band at ~80 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Cytoskeleton, Plasma Membrane, Cell Membrane, Peripheral Membrane Protein, Cytoplasmic Side, Cytosol, Axon, Microtubule, Microtubule Associated Complex, Tubulin Complex, Nucleus, Nuclear Periphery, Nuclear Speck, Axolemma Plasma Membrane, Axolemma, C |
Tissue Specificity: |
Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
Accession Number: |
NP_001116538.2 |
Gene ID: |
4137 |
Swiss-Prot: |
P10636 |
Field of Use: |
For in vitro research use only. |