TAUT (G594) polyclonal Antibody | BS9162

TAUT (G594) polyclonal Antibody | BS9162 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT) . TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNFα upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TAUT (G594) polyclonal Antibody detects endogenous levels of TAUT rotein.

Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; SLC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 (neurotransmitter transporter; taurine) ; member 6; Solute carrier family 6 member 6; TAUT;

Immunogen: Synthetic peptide, corresponding to amino acids 570-620 of Human TAUT.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A