TBCA Antibody | 14-766

TBCA Antibody | 14-766 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TBCA (NP_004598.1) .

Research Area: Cell Cycle, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: OVCAR3

Positive Control 2: HeLa

Positive Control 3: 293T

Positive Control 4: U-87MG

Positive Control 5: Mouse testis

Positive Control 6: N/A

Molecular Weight: Observed: 13kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.