TBX21 Antibody | 7477

TBX21 Antibody | 7477 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2.
The immunogen is located within the last 50 amino acids of TBX21 .

Research Area: Immunology

Tested Application: E, WB, IF

Application: TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: TBX21 antibody is human and mouse reactive.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: Cat. No. 17-010 - HEK293 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 59 kDa
Observed: 55kDa

Validation: N/A

Isoform: N/A

Purification: TBX21 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TBX21 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TBX21 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: TBX21 Antibody : TBET, T-PET, T-bet, TBLYM, TBET, T-box transcription factor TBX21, T-cell-specific T-box transcription factor T-bet, T-box protein 21

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1, 2) . Members of this family include transcription factors involved in the regulation of developmental processes (2) . Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1, 3) . Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3) .