Additional Information
Size: |
100 µg |
Target: |
TCF7L2 |
Conjugate: |
ATTO 488 |
Research Area: |
Cell Signaling | Epigenetics and Nuclear Signaling | Transcription | Domain Families | Hmg box | Cardiovascular System | Atherosclerosis | Diabetes Associated | Metabolism |
Alternative Name: |
Transcription factor 7-like 2 antibody, HMG box transcription factor 4 antibody, hTCF 4 antibody, hTCF-4 antibody, T cell factor 4 antibody, T cell specific HMG box antibody, T cell specific transcription factor 4 antibody, T-cell factor 4 antibody, |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic peptide of Human TCF7L2 (400-500 aa), conjugated to Keyhole Limpet Haemocyanin (KLH). |
Immunogen Species: |
Human |
Applications: |
WB, IHC |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human, Rat |
Antibody Dilution: |
WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide |
Concentration: |
1 mg/ml |
Specificity: |
Detects 68 kDa, band at ~55 kDa is another isoform, band at ~75 kDa is due to post translational modification. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
A 1:1000 dilution of SPC-722 was sufficient for detection of TCF7L2 in 15 µg of rat kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. |
Cellular Localization: |
Nucleus, Pml Body |
Tissue Specificity: |
Detected in epithelium from small intestine, with the highest expression at the top of the crypts and a gradient of expression from crypt to villus. Detected in colon epithelium and colon cancer, and in epithelium from mammary gland and carcinomas de |
Accession Number: |
NP_001139746.1 |
Gene ID: |
6934 |
Swiss-Prot: |
Q9NQB0 |
Field of Use: |
For in vitro research use only. |
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