Description
TCP1 Polyclonal Antibody | E-AB-40159 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: AI528772, c-cpn, CCT alpha, CCT, CCT-alpha, CCT1, Ccta, CCTalpha, D6S230E, MGC133746, p63, T complex 1, T complex protein 1 alpha subunit, T complex protein 1, T-complex homolog TCP1, T-complex protein 1 subunit alpha, T-complex protein 1 subunit alpha B, Tailless complex polypeptide 1, Tailless complex polypeptide 1A, Tailless complex polypeptide 1B, TCP 1 alpha, Tcp-1, TCP-1-alpha, TCP1, TCPA, Tp63, TRic
Application: WB
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant human T-complex protein 1 subunit alpha protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:50-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 60 kDa
Molecular Weight(Observed): 60 kDa