Description
TCTP polyclonal Antibody | BS91325 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC FC IP
Application Range: WB:1:500-1:2,000 ICC/IF:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: TCTP polyclonal Antibody detects endogenous levels of TCTP protein.
Molecular Weight: 20 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TCTP, HRF, TPT1, FLJ27337, Fortilin, Histamine releasing factor, Histamine-releasing factor, HRF, Immunoglobulin E-dependent, p02, p23, TCTP, TCTP, tpt1, Translationally controlled tumor protein, Translationally-controlled tumor protein, Tumor protein translationally controlled 1, tumor protein, translationally-controlled 1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: