Tenofovir disoproxil fumarate | 1920

A water-soluble diester prodrug of the active ingredient Tenofovir, that belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people.

Tenofovir disoproxil fumarate is a water-soluble diester prodrug of the active ingredient Tenofovir, that belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people.

1920 | Tenofovir disoproxil fumarate DataSheet

Alternate Name/Synonyms: 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)-phosphinyl)methoxy)propyl)adenine fumarate

Appearance: White solid

Formulation: N/A

CAS Number: 202138-50-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₃₀N₅O₁₀P. C₄H₄O₄

Molecular Weight: 653.51

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: Water (>10 mg/ml)

Handling: Protect from air and mositure

Country of Origin: USA

Tag Line: A reverse transcriptase inhibitor

MDL Number: MFCD08141829

PubChem CID: 6398764

SMILES: CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OCOC(=O)OC(C)C.C(=CC(=O)O) C(=O)O

InChi: InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27, 32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24; 5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H, 7,8)/b;2-1+/t14-;/m1./s1

InChi Key: VCMJCVGFSROFHV-WZGZYPNHSA-N