Tensin-1 (phospho-Y483) polyclonal Antibody | BS4831

Tensin-1 (phospho-Y483) polyclonal Antibody | BS4831 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: IHC

Application Range: IHC: 1:50~1:200

Background: Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: p-Tensin-1 (Y483) polyclonal Antibody detects endogenous levels of Tensin-2 protein when phosphorylated at Tyr483.

Molecular Weight: ~ 152, 230 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tensin-1; TNS1; TNS

Immunogen: Synthetic phosphopeptide derived from human Tensin-1 around the phosphorylation site of Tyrosine 483.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Tumor Angiogenesis,