Tetracycline Hydrochloride | B1535

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic. It has been used in studies of multidrug resistance and potential side effects including acute pancreatitis.

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic. It has been used in studies of multidrug resistance and potential side effects including acute pancreatitis.

B1535 | Tetracycline Hydrochloride DataSheet

Alternate Name/Synonyms: (4S,4aS,5aS,6S,12aS)- 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride

Appearance: Yellow solid

Formulation: N/A

CAS Number: 64-75-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₂H₂₄N₂O₈·HCl

Molecular Weight: 480.9

Cell-Permeable?: Yes

Purity: ≥95%

Solubilities: H₂O (>50 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis.

MDL Number: MFCD00078142

PubChem CID: 54704426

SMILES: CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl

InChi: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

InChi Key: YCIHPQHVWDULOY-FMZCEJRJSA-N