TF | Transferrin | IMS02-020-322

TF | Transferrin | IMS02-020-322 | Gentaur UK, US & Europe Distribution

Immunogen: purified full length native protein UniProt: P02787

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified IgY in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1% sodium azide., pH 7.2.

Format: Liquid

Tested Application: Affinity purified IgY

Related Products: IMS06-020-323 | Anti-TF | transferrin, hen antibody labelled with biotin, chicken antibodiesAS10 1370 | Anti-TF | transferrin, goat antibodiesSecondary antibodies

Recommended Dilutions: 1 : 1000 (WB)

Molecular weight: 77 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Primates

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Only one precipitin arc in immunodiffusion against normal human serum, dilution 1: 10, or human transferrin, Only one precipitin arc in immunoelectrophoresis against normal human serum, or human transferrin

Background: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Reconstitution: N/A

Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Immunology

Research Area: Immunology