TFE3 Antibody | XW-7695

TFE3 Antibody | XW-7695 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: 432-541

Research Area: Other

Tested Application: WB

Application: Transcription factor E3 antibody can be used for the detection of Transcription factor E3 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 80 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: TFE3 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: BHLHE33, Transcription factor E3, Class E basic helix-loop-helix protein 33, bHLHe33, TFEA, RCCP2, RCCX1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Positive-acting transcription factor that binds to the immunoglobulin enchancer MUE3 motif. It binds also very well to a USF/MLTF site. Binding of TFE3 to DNA induces DNA binding.

DISEASE: Chromosomal aberrations involving TFE3 may be a cause of papillary renal cell carcinoma (PRCC) . Translocation t (X;1) (p11.2;q21.2) with PRCC; translocation t (X;1) (p11.2;p34) with PSF; inversion inv (X) (p11.2;q12) that fuses NONO to TFE3.