TFIIB monoclonal Antibody | MB0045

TFIIB monoclonal Antibody | MB0045 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB IHC ICC

Application Range: WB: 1:1000 ICC: 1:50~200 IHC: 1:500

Background: Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Template commitment is established by the initial binding of TFIID to the “TATA” element of the promotor, a step which may be facilitated by TFIIA. TFIIB then acts as the bridge between TFIID and RNA polymerase II.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of TFIIB and does not cross-react with related proteins

Molecular Weight: Predicted band size:35KDa Observed band size:37KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TF2B; TFIIB; S300-II; Transcription initiation factor IIB

Immunogen: Recombinant full length Human TFIIB.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: