TGF-beta3, human recombinant | 4344

Transforming growth factor 3 (TGF-3) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Recombinant human TGF-3 is a 25 kDa protein with each subunit containing 112 amino acid residues.

4344 | TGF-beta3 human recombinant DataSheet

Biomolecule/Target: TGF-beta 3

Synonyms: Transforming Growth Factor-2, Human TGF-3, TGF-3,TGF3, TGF 3, h-TGF-3, rh-TGF-3, recombinant human TGF-3, recombinant TGF-, TGF

Alternates names: Platelet-Derived Growth Factor-CC

Taglines: A protein that controls proliferation, cellular differentiation, & other functions in most cells

NCBI Gene ID #: 56034

NCBI Gene Symbol: PDGFC

Gene Source: Human

Accession #: Q9NRA1

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 15-20 ng/ml.

Biological activity: Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 15-20 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 25 kDa

Concentration: N/A

Appearance: Liquid protein

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Sodium citrate, pH 3.0

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: MVVDLNLLTE EVRLYSCTPR NFSVSIREEL KRTDTIFWPG CLLVKRCGGN CACCLHNCNE CQCVPSKVTK KYHEVLQLRP KTGVRGLHKS LTDVALEHHE ECDCVCRGST GG