TGFB1 Antibody [APR10406G]

TGFB1 Antibody [APR10406G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This TGFB1 antibody is generated from a rabbit immunized with a recombinant protein of human TGFB1.

Cellular Localisation: [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix

Molecular Weight: 44341

Clone: Polyclonal

Gene Name: TGFB1 (HGNC:11766)

Gene ID: 7040

Function: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.

Summary: Tissue Location: Highly expressed in bone (PubMed:11746498, PubMed:17827158) . Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158) . Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB