TGFBR1 Antibody | 16-823

TGFBR1 Antibody | 16-823 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human TGFBR1.

Research Area: Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: SW480

Positive Control 3: 22Rv1

Positive Control 4: mouse brain

Positive Control 5: rat brain

Positive Control 6: N/A

Molecular Weight: Observed: 56kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: activin A receptor type II-like kinase, 53kD, TGF-beta type I receptor, TGF-beta receptor type-1, TGF-beta receptor type I, TGFR-1, SKR4, LDS2A, LDS1A, ALK5, ALK-5, ACVRLK4, AAT5, transforming growth factor, beta receptor 1, TGFBR1, transforming growth factor-beta receptor type I, beta receptor I (activin A receptor type II-like kinase, 53kD) , transforming growth factor beta receptor I, tbetaR-I, serine/threonine-protein kinase receptor R4, activin receptor-like kinase 5, activin A receptor type II-like kinase, 53kDa

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.