TGS1 polyclonal Antibody | BS70955

TGS1 polyclonal Antibody | BS70955 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m (2,2,7) G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs) . Plays a role in transcriptional regulation

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TGS1 polyclonal Antibody detects endogenous levels of TGS1 protein.

Molecular Weight: ~ 97 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PIMT; PIPMT; TGS1; HCA137; NCOA6IP; PIMT

Immunogen: Recombinant protein of human TGS1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: