THAP11 Antibody | 7613

THAP11 Antibody | 7613 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Immunogen: THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11.
The immunogen is located within the last 50 amino acids of THAP11.

Research Area: Stem Cell

Tested Application: E, WB

Application: THAP11 antibody can be used for detection of THAP11 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: THAP11 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1303 - Human Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 35 kDa
Observed: 38 kDa

Validation: N/A

Isoform: N/A

Purification: THAP11 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: THAP11 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: THAP11 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: THAP11 Antibody: RONIN, CTG-B43a, CTG-B45d, HRIHFB2206, THAP domain-containing protein 11

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The THAP domain-contining protein 11 (THAP11) , also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1) . THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2) . THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly (rC) binding protein PCBP1 (3) .