Thapsigargin | 1558

Potent, cell permeable IP3-independent intracellular calcium releaser; Inhibits microsomal Ca2+-ATPase; Stimulates arachidonic acid metabolism in macrophages.

Thapsigargin is a potent, cell permeable IP3-independent intracellular calcium releaser; Inhibits microsomal Ca²⁺-ATPase; Stimulates arachidonic acid metabolism in macrophages.

1558 | Thapsigargin DataSheet

Alternate Name/Synonyms: Thapsigargin

Appearance: Coloreless solid

Formulation: N/A

CAS Number: 67526-95-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₄H₅₀O₁₂

Molecular Weight: 650.76

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO or 100% EtOH

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A calcium releaser

MDL Number: MFCD00083511

PubChem CID: 446378

SMILES: CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O

InChi: InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1

InChi Key: IXFPJGBNCFXKPI-FSIHEZPISA-N