THBD Antibody (C-Term) [APR33527G]

THBD Antibody (C-Term) [APR33527G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This THBD antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 537-571 amino acids from human THBD.

Cellular Localisation: Membrane; Single-pass type I membrane protein.

Molecular Weight: 60329

Clone: Polyclonal

Gene Name: THBD

Gene ID: 7056

Function: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Summary: Tissue Location: Endothelial cells are unique in synthesizing thrombomodulin

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM