THDOC | Tetrahydrodeoxycorticosterone | AS06 192

THDOC | Tetrahydrodeoxycorticosterone | AS06 192 | Gentaur UK, US & Europe Distribution

Immunogen: BSA-coupled THDOC

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.

Format: Liquid

Tested Application: Radioimmunoassay (RIA)

Related Products: N/A

Recommended Dilutions: 1 : 1000 (RIA)

Molecular weight: N/A

Confirmed Reactivity: THDOC

Predicted Reactivity: N/A

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: TetraHydroDesOxyCorticosterone (THDOC) is a stress related neuroactive steroid. THDOC is a metabolite of desoxycoritcosterone (DOC) and progesterone and DOC is a steroid in the synthesis pathway to aldosterone. THDOC is produced by the adrenal in parallel with cortisol at stress and is regulated by ACTH. THDOC is a potent positive modulator of the GABA A receptor. THDOC passes the blood-brain barrier and can be found in the brain after stress in nanomolar concentrations.

Reconstitution: N/A

Storage: Store at 4°C or at -20°C for long-term storage; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Neurobiology

Research Area: Neurobiology