THEM2 Antibody [AMM08196G]

THEM2 Antibody [AMM08196G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This THEM2 monoclonal antibody is generated from mouse immunized with THEM2 recombinant protein.

Cellular Localisation: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9CQR4}. Mitochondrion {ECO:0000250|UniProtKB:Q9CQR4}. Nucleus {ECO:0000250|UniProtKB:Q9CQR4} Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9CQR4} Note=During interphase, found both in the nucleus and in the cytoplasm At mitosis, localizes to the spindle. Colocalizes with tubulin {ECO:0000250|UniProtKB:Q9CQR4}

Molecular Weight: 14960

Clone: Monoclonal

Gene Name: ACOT13 (HGNC:20999)

Gene ID: 55856

Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545) . Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (By similarity) (PubMed:16934754, PubMed:19170545) . Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3, 4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity) (PubMed:16934754, PubMed:19170545) . May play a role in controlling adaptive thermogenesis (By similarity) .

Summary: N/A

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Acyl-coenzyme A thioesterase 13, Acyl-CoA thioesterase 13, 312-, Thioesterase superfamily member 2, Acyl-coenzyme A thioesterase 13, N-terminally processed, ACOT13, THEM2